Publications


Journal Publications

Susan Eagle, M.D. et al., Surgical skin markers impair human saphenous vein graft smooth muscle and endothelial function. The American Surgeon 77(7): 922-928 (2011).

Kyle M. Hocking, BE et al., Detrimental effects of mechanical stretch on smooth muscle function in saphenous veins. Journal of Vascular Surgery 53(2): 454-460 (2011).

Michael J. Osgood, MD et al.Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein. Journal of Vascular Surgery 60(1): 202-211 (2014).

Fan Dong Li, PhD et al., Pressure control during preparation of saphenous veins. JAMA Surg. 149(7), 655-62 (2014).

Ralf E. Harskamp, MD et al. Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from PREVENT IV randomized clinical trial. JAMA Surg. 149(8):798-805 (2014)

Igor V. Voskresensky, MD et al., Brilliant blue FCF as an alternative dye for saphenous vein graft marking: effect on conduit function. JAMA Surg. 149(11):1176-81(2014)

Wise ES, et al. Preservation solution impacts physiologic function and cellular viability of human saphenous vein graft. Surgery (2015) May 20.

Hocking KM et al. Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury. Journal of Vascular Surgery (2015) Feb 19.

Eric S. Wise, MD et al., An Optimized Preparation Technique for Saphenous Vein Graft, The American Surgeon 81(7): 274-6

Abstracts

Osgood MJ, Hocking KM, Sexton KW, Komalavilas P, Cheung-Flynn J, Eagle S, Leacche M, Brophy C. Surgical skin markers reduce human saphenous vein graft functional viability. Southeastern Surgical Congress, Chattanooga, TN, February 2011.

Sexton KW, Hocking KM, Osgood MJ, Komalavilas P, Cheung-Flynn J, Eagle S, Leacche M, Brophy C. Basal intimal thickness predicts endothelial function in human saphenous vein. J Surg Res 2011;165(2):343.

Osgood MJ, Hocking KM, Sexton KW, Cheung-Flynn J, Komalavilas P, Leacche M, Eagle S, Brophy C. “Back-table” manipulation of human saphenous vein significantly impairs endothelial and smooth muscle function. Arteriosclerosis Thrombosis and Vascular Biology 2011 Scientific Sessions, Chicago, IL 04/11.

Eagle S, Li F, Hocking K, Osgood M, Sexton K, Komalavilas P, Cheung-Flynn J, Brophy C. Preservation of endothelial function and prevention of intimal hyperplasia in porcine saphenous vein with a pressure-release valve. Arteriosclerosis Thrombosis and Vascular Biology 2011 Scientific Sessions, Chicago, IL 04/11.

Osgood MJ, Hocking KM, Sexton KW, Cheung-Flynn J, Komalavilas P, Leacche M, Eagle S, Brophy C. “Back-table” manipulation of human saphenous vein significantly impairs endothelial and smooth muscle function. Annual Vascular Meeting Chicago, IL, June 16-18 2011.

Osgood MJ, Sexton KW, Hocking KM, Voskresensky IV, Eagle S, Cheung-Flynn J, Komalavilas P, Brophy CM. Inhibition of vein graft intimal hyperplasia with a blue marking dye in a rabbit carotid interposition model. 7th Annual Academic Surgical Congress 2012.

Osgood MJ, Dikalov S, Hocking KM, Cheung-Flynn J, Voskresensky I, Komalavilas P, Harrison DG, Brophy CM. Oxidative stress, a mediator of human saphenous vein bypass graft dysfunction. Circulation 2012;126:A11385.

Voskresensky I, Hocking K, Osgood M, Cheung-Flynn J, Komalavilas P, Brophy .  Increased lysine acetylation after back-table preparation of human saphenous vein.  ATVB, Orlando Fl 2013

Wise, Eric S, song Jun, Voskrensensky I, Corsa B, Eagle S, Brophy C, Cheung-Flynn J.  Metabolic effects of graft preparation techniques on saphenous veins, NAVBO, Hyannis, MA 2013

Feldman Dan, Cheung-Flynn J, Komalavilas P, Brophy C.  Standard surgical preparation increases apoptosis and reduced physiologic responses of human saphenous vein grafts used for CABG.  NAVBO Hyannis MA 2013

Hocking KM, Brophy CM, Cheung-Flynn J. Surgical vein graft preparation inhibits nitric oxide bioavailability in porcine saphenous vein. International Society for Applied Cardiovascular Biology, Cleveland, OH, April 2014

ES Wise, MD; KM Hocking, PhD; P Komalavilas, PhD; J Cheung-Flynn, PhD; CM Brophy, Preservation in Acidic Normal Saline Solution Decreases Saphenous Vein Viability.  MD American Surgical Congress/ Society for University Surgeons Annual Meeting, February 2015 Las Vegas, NV